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Sunday, July 12, 2020 | History

2 edition of Radionuclide metabolism and toxicity found in the catalog.

Radionuclide metabolism and toxicity

Radionuclide metabolism and toxicity

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  • 24 Currently reading

Published by Masson in Paris .
Written in English

    Subjects:
  • Radioisotopes -- Metabolism -- Congresses,
  • Radioisotopes -- Toxicology -- Congresses

  • Edition Notes

    Statementedited by P. Galle, R. Masse ; pref. by M. Tubiana.
    ContributionsGalle, P., Masse, R.
    Classifications
    LC ClassificationsRA1231R2 R38
    The Physical Object
    Pagination321 p. :
    Number of Pages321
    ID Numbers
    Open LibraryOL21115118M
    ISBN 10222578034X

      The purpose of this book is to enhance the current knowledge of pharmacology of the newborn by observing the embryo and placenta in normal and abnormal development, placental transfer of drugs, metabolic pathways, and metabolism of specific drugs such as theophylline, benzodiazepines, and antibiotics.   The transcription factor (nuclear factor-erythroid 2 prelated factor 2, NRF2) is a master regulator of the cellular response to oxidative insults. While antioxidant response enzymes are well-characterized transcriptional targets of NRF2, it is recently becoming clear that NRF2 also supports cellular detoxification through metabolic rewiring to support the antioxidant .

      Toxic Phosphorus Esters: Chemistry, Metabolism, and Biological Effects aims to become a source book on organophosphate research and show how the understanding of the events following organophosphate poisoning of animals can be understood in terms of events at the molecular level. The manuscript first offers information on nonenzymic reactions and the .   The Metabolism and Toxicity of Fluoride (Monographs in Oral Science, Vol. 16): Medicine & Health Science Books @

    Since the first edition of this highly-acclaimed book appeared in , a considerable amount of new information has been published on the diverse effects that fluoride can produce in biological systems. The remarkable decline in dental caries that is now occurring throughout the world can be largely attributed to the use of ingested and topical fo. Malathion (O,O-dimethyl-S-1,2-bis ethoxy carbonyl ethyl phosphorodithionate) is a non-systemic, wide-spectrum pesticide. It is widely used throughout the world for agricultural, residential, and public health purposes, mainly to enhance food production and to provide protection from disease vectors. Malathion preference over other organophosphate pesticides relates to its low .


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Radionuclide metabolism and toxicity Download PDF EPUB FB2

Age-Related Factors in Radionuclide Metabolism and Dosimetry: Radiation Protection Programme and the Commissariat à l'Energie Atomique, Institut de Protection et de Sûreté Nucléaire, Fontenay-aux-Roses, France Volume 13 of Developments in Nuclear Medicine: Editors: G.B.

Gerber, H. Métivier, H. Smith: Edition: illustrated: Publisher. Get this from a library. Radionuclide metabolism and toxicity: proceedings of the symposium organized in by the Société française de biophysique et de médecine nucléaire and IRU-environnement de l'Université Paris-Val de Marne.

[P Galle; R Masse; Société française de biophysique et de médicine nucléaire.; Université Paris-Val-de-Marne. The risk of chemical toxicity of U, a nonessential and toxic natural radionuclide, is higher than that of radiation toxicity due to its half-life of up to × 10 9 y (Sheppard et al., ).

In Chlamydomonas reinhardtii, U induced abnormal chlorophyll fluorescence and damaged the photosynthetic electron transport chain (Herlory et al., ).Author: Yu Zhang, Jin-Long Lai, Xiao-Hui Ji, Xiao-Hui Ji, Xue-Gang Luo. Purchase Mechanisms of Toxicity and Metabolism - 1st Edition.

Print Book & E-Book. ISBNBook Edition: 1. Factors affecting drug metabolism, such as genetic polymorphisms, age and diet are discussed and how metabolism can lead to toxicity is explained.

The book concludes with the role of drug metabolism in the commercial development of therapeutic agents as well as the pharmacology of some illicit drugs. @article{osti_, title = {Metabolism and effects of uranium in animals}, author = {Durbin, P W and Wrenn, M E}, abstractNote = {This paper summarizes the results of animal experiments that are the foundation of our current understanding of the biological behavior or uranium.

Topics discussed include: metabolism including biological transport, excretion, deposition and. Radiation Toxicity: A Practical Guide brings together renowned authors from Radionuclide metabolism and toxicity book cancer centers.

Radiation, medical and surgical oncologists, nursing professionals, and members of radiation oncology teams will find this book an important reference. "Radiation therapy is an essential component of cancer treatment. Joann Scatina, PhD, has over twenty-four years of drug metabolism experience, and is currentlyVice President of the Drug Metabolism Division, Drug Safety and Metabolism, for WyethResearch.

Scatina's research interests include identification of metabolites, metabolicpathways and enzymes responsible, in vitro-in vivo extrapolation, and.

The science of toxicology has a dual nature. It is the study of mechanisms by which environmental agents exert their toxic effects, and it is the empirical definition of the magnitude of toxicity of such agents and the risk they present to exposed human populations.**For detailed descriptions of general toxicology, see Hayes () and Klaassen et al.

More specifically, Williams. The Toxicity of Plutonium, Americium and Curium provides a biological basis for an assessment of the radiological health problems resulting from human exposure to americium, curium, and plutonium.

This book discusses the method of injection of the chelating agent DTPA for removing soluble forms of americium, curium, and plutonium. This book,provides extensive coverage of safety evaluation of new pharmaceutical compounds and risk characterization of chemicals using the guidelines of regulatory agencies.

The contributors of this book are highly qualified and considered authorities in toxicology in general, and reproductive and developmental toxicology, in particular. This chapter discusses the methods used to evaluate the toxicity of a substance for the purpose of health risk assessment.

Evaluation of toxicity involves two steps: hazard identification and dose-response evaluation. Hazard identification includes a description of the specific forms of toxicity (neurotoxicity, carcinogenicity, etc.) that can be caused by a chemical and an.

Handbook of Toxicology of Chemical Warfare Agents, Second Edition covers every aspect of deadly toxic chemicals used in conflicts, warfare and terrorism.

Including findings from experimental as well as clinical studies, this essential reference offers in-depth coverage of individual toxicants, target organ toxicity, major incidents, toxic effects in humans, animals. Book Description Table of Contents Editor(s) Book Description Published in Chromium is important in medicine because of its widespread use (abouttons are processed in the U.S.

each year), toxicity, carcinogenic effect, and its high sensitization index in low concentration. Once in an organism, chemicals are either metabolized or stored. Metabolism includes both toxic effects and detoxification.

In addition to metabolism, storing chemicals in inert material can be considered a detoxification mechanism. On the other hand, release of toxic chemicals from inert material can cause delayed toxicity.

The metabolism and toxicity of fluoride by Gary M. Whitford,Karger edition, in English - 2nd, rev. Until now, the area of drug metabolism and pharmacokinetics has been lacking in texts written for the Medicinal Chemist. This outstanding book, aimed at postgraduate medicinal chemists and those working in industry, fills this gap in the literature.

Written by medicinal chemists and ADMET scientists with a combined experience of around years, this aid to discovering drugs.

Metabolism and detoxification protect liver from injury by drugs and toxic metabolites. This article will briefly summarize the major metabolic pathways and their regulation in maintaining.

The purpose of this book is to enhance the current knowledge of pharmacology of the newborn by observing the embryo and placenta in normal and abnormal development, placental transfer of drugs, metabolic pathways, and metabolism of specific drugs such as theophylline, benzodiazepines, and antibiotics.

Essential and Toxic Trace Elements and Vitamins in Human Health is a comprehensive guide to the wide variety of micronutrients that affect human health, including fat-soluble and water-soluble vitamins that support diverse biochemical functions, trace elements with established and suggested links to health maintenance, and elements with known.

Effects and Metabolism of Toxic Trace Metals in the Neonatal Period. Harold H. Sandstead, Richard A. Doherty, Kathryn A. Mahaffey special reference to absorption, excretion and biological half-times.

The effects and dose-response relationships of toxic metals, including a discussion of general principles, was the second major topic.Drug metabolism and drug toxicity.

New York: Raven Press, © (OCoLC) Online version: Drug metabolism and drug toxicity. New York: Raven Press, © (OCoLC) Material Type: Conference publication: Document Type: Book: All Authors / .The cyclotron-produced radionuclide, 13N, was used to label ammonia and to study its metabolism in a group of 5 normal subjects and 17 patients with liver disease, including 5 with portacaval shunts and 11 with encephalopathy.

Arterial ammonia levels were micron.